Blood pressure profile and endothelial function in restless legs syndrome

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Sensory profile in primary restless legs syndrome and restless legs syndrome associated with small fibre neuropathy.

Sir, The association of restless legs syndrome with polyneuropathy, especially with involvement of small sensory fibres, is suggested by several observations (Iannaccone et al., 1995; Polydefkis et al., 2000; Gemignani et al., 2006); however, it is still controversial (Hattan et al., 2009). Bachmann et al. (2010) investigated 34 consecutive outpatients with restless legs syndrome from their Mov...

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The restless legs syndrome.

The first description of the restless legs syndrome (RLS) is attributed to Thomas Willis in the 'London Practice of Physick' of 1685 (Ekbom, 1960). Here he wrote 'wherefore to some, when being a bed they betake themselves to sleep, presently in the arms and leggs, leapings and contractions of their tendons, and so great a restlessness and tossings of their members ensue, that the diseased are n...

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Restless legs syndrome.

Restless legs syndrome is common; it is characterised by an urge to move and usually, but not exclusively, affects the legs. This urge to move is typically accompanied by abnormal sensations, variably described as burning, tingling, aching, or “insects crawling under the skin.” These sensations are transiently or partially relieved by movement, and there is a strong circadian influence—symptoms...

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[Restless legs syndrome].

The restless legs syndrome (RLS) is a common neurological disorder to take possession of increasing attention. RLS is characterized by an urge to move the legs, usually accompanied by uncomfortable or unpleasant sensations, that occurs or worsen at rest and is relieved by activity. The symptoms of RLS have a major impact on nocturnal sleep and daytime functions. The clinical diagnostic criteria...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2019

ISSN: 2045-2322

DOI: 10.1038/s41598-019-52401-4